Plagued by headache pain? New research suggests that Botox injections might benefit people who suffer from low cerebrospinal fluid (CSF) headaches -- a very specific condition. But the study also opens up the possibility that Botox is more broadly applicable in treating serious headaches than previously thought. The study, co-written by Michal Cutrer, M.D., a Mayo Clinic neurologist, centered on a patient who had suffered from CSF headaches for more than 20 years. With CSF, headaches are caused by internal spinal fluid leaks, which lower the pressure in part of the brain and cause it to sag downwards when the patient is standing or sitting upright. Though pain levels range from person to person, the patient from the Mayo Clinic study had dealt with debilitating headaches for half her life. “She had extremely intense pain that would only improve when she lay flat,” Cutrer explained, “So she really had been disabled for years, and had been to many, many docto...